Big science is the future of science research, but how can science centres position themselves as the big science communicators? Large scale multinational science projects are becoming the norm. These include, to name but a few, the Square Kilometre Array, the Human Brain Project, citizen science projects, and biotechnology. Communicating big science requires science centres to engage with stakeholders and policy makers at all levels, both within and outside of the respective project. It aims to amalgamate all these various different cohorts into a shared vision and understanding, striving towards an active inclusion of various perceptions, concerns and the ultimate outcome expected for each cohort. This session will explore how science centres work collaboratively, both with each other and other stakeholders, to co-create an effective framework for communicating big science. What collaboration and co-design framework should be adopted for effectively communicating big science?